Sketchbook on iPad and Adobe Illustrator and Photoshop.
300 dpi version at https://www.spoonflower.com/designs/16193189 450 dpi version at https://www.spoonflower.com/designs/16193173 600 dpi verstion at https://www.spoonflower.com/designs/16193167 Original set for sale at https://www.spoonflower.com/designs/16041960 see a cross stitch version of this at https://www.spoonflower.com/designs/16165988